J2323Natalizumab injection
Published CMS Medicare Part B payment-limit context for J2323, with recent quarterly history and calculated package-level strength context from the CMS crosswalk.
CMS payment limit
$24.406
per 1 MG · Medicare Part B
Up 0.3%from $24.321 in 2026-Q2
- Current quarter
- Billing unit
Payment limit over time
$24.6005$23.7915
2024-Q4: $24.154; 2025-Q1: $23.88; 2025-Q2: $24.368; 2025-Q3: $24.126; 2025-Q4: $23.996; 2026-Q1: $24.512; 2026-Q2: $24.321; 2026-Q3: $24.406
No current FDA shortage matchThe latest completed FDA data has no affected record matching the Natalizumab ingredient family (FDA data as of August 20, 2026).
Tysabri
Package figures are calculated from the CMS per-unit payment limit × billable units per package; they are not CMS-published package-level payment limits.
Other Natalizumab presentations
1 other CMS codeSource-linked same ingredient-family context, not recommendations, substitutes, or clinical or billing equivalence.
Swipe to see all columns
| HCPCS | CMS description | Current quarter 2026-Q3 | Prior quarter 2026-Q2 | Change | NDCs | View history |
|---|---|---|---|---|---|---|
| Q5134 | Inj, tyruko, 1 mg | $24.494 per 1 MG | $24.321 per 1 MG | Up 0.7% |
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